Molecular imaging allows the non invasive assessment and monitoring of disease specific biological/molecular processes in vivo. Therefore, several techniques i.e. magnetic resonance, radionuclide or optically based imaging procedures are applied.
For analysis of novel therapy approaches by imaging strategies, we use adequate molecular reporter systems, but also multimodal imaging techniques are applied. We utilise the advantages of several imaging approaches complementarily to achieve the most accurate answer to our scientific problems. Magnetic resonance tomography (MRI) e.g. is characterised by its high spatial resolution whereas positron emission tomography (PET) is featured by a high sensitivity and definite quantification. The optical imaging approaches (Optical Imaging) allow the direct transfer of cell biological findings to in vivo applications. To validate the imaging data, we use invasive techniques, like immunohistochemistry and autoradiography.