Publications of Wulf Paschen

Paschen, W.; Proud, C. G.; Mies, G.: Shut-down of translation, a global neuronal stress response: mechanisms and pathological relevance. Current Pharmaceutical Design 13 (18), pp. 1887 - 1902 (2007)

Aufenberg, C.; Wenkel, S.; Mautes, A.; Paschen, W.: Spinal cord trauma activates processing of xbp1 mRNA indicative of endoplasmic reticulum dysfunction. Journal of Neurotrauma 22 (9), pp. 1018 - 1024 (2005)

Schneeloch, E.; Wenkel, S.; Mies, G.; Paschen, W.: Spreading depression activates unfolded protein response. Neuroscience Letters 368 (1), pp. 37 - 40 (2004)

Paschen, W.; Hayashi, T.; Saito, A.; Chan, P. H.: GADD34 protein levels increase after transient ischemia in the cortex but not in the CA1 subfield: implications for post-ischemic recovery of protein synthesis in ischemia-resistant cells. Journal of Neurochemistry 90 (3), pp. 694 - 701 (2004)

Paschen, W.: Endoplasmic reticulum dysfunction in brain pathology: Critical role of protein synthesis. Current Neurovascular Research 1 (2), pp. 173 - 181 (2004)

Paschen, W.; Yatsiv, I.; Shoham, S.; Shohami, E.: Brain trauma induces X-box protein 1 processing indicative of activation of the endoplasmic reticulum unfolded protein response. Journal of Neurochemistry 88 (4), pp. 983 - 992 (2004)

Paschen, W.: Search for common denominators of neuronal cell injury in stroke and degenerative diseases. Journal of Neurochemistry 87 (Suppl. 1), p. 8 - 8 (2003)

Paschen, W.: Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain. Cell Calcium 34 (4-5), pp. 365 - 383 (2003)

Paschen, W.: Mechanisms of neuronal cell death: diverse roles of calcium in the various subcellular compartments. Cell Calcium 34 (4-5), pp. 305 - 310 (2003)

Paschen, W.; Mengesdorf, T.: Conditions associated with ER dysfunction activate homer 1a expression. Journal of Neurochemistry 86 (5), pp. 1108 - 1115 (2003)

Paschen, W.: Shutdown of translation: Lethal or protective? Unfolded protein response versus apoptosis. Journal of Cerebral Blood Flow and Metabolism 23 (7), pp. 773 - 779 (2003)

Paschen, W.; Aufenberg, C.; Hotop, S.; Mengesdorf, T.: Transient cerebral ischemia activates processing of xbp1 messenger RNA indicative of endoplasmic reticulum stress. Journal of Cerebral Blood Flow and Metabolism 23 (4), pp. 449 - 461 (2003)

Paschen, W.; Hotop, S.; Aufenberg, C.: Loading neurons with BAPTA-AM activates xbp1 processing indicative of induction of endoplasmic reticulum stress. Cell Calcium 33 (2), pp. 83 - 89 (2003)

Paschen, W.; Mengesdorf, T.; Proud, C. G.; Mies, G.: Mechanisms underlying irreversible shut down of translation in transient focal cerebral ischemia in mouse brain. Stroke 34 (1), p. 299 - 299 (2003)

Mengesdorf, T.; Jensen, P. H.; Mies, G.; Aufenberg, C.; Paschen, W.: Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease? Proceedings of the National Academy of Sciences of the United States of America 99 (23), pp. 15042 - 15047 (2002)

Mengesdorf, T.; Proud, C. G.; Mies, G.; Paschen, W.: Mechanisms underlying suppression of protein synthesis induced by transient focal cerebral ischemia in mouse brain. Experimental Neurology 177 (2), pp. 538 - 546 (2002)

Mengesdorf, T.; Althausen, S.; Paschen, W.: Genes associated with pro-apoptotic and protective mechanisms are affected differently on exposure of neuronal cell cultures to arsenite. No indication for endoplasmic reticulum stress despite activation of grp78 and gadd153 expression. Molecular Brain Research 104 (2), pp. 227 - 239 (2002)

Mengesdorf, T.; Althausen, S.; Mies, G.; Olah, L.; Paschen, W.: Phosphorylation state, solubility, and activity of calcium/calmodulin-dependent protein kinase II alpha in transient focal ischemia in mouse brain. Neurochemical Research 27 (6), pp. 477 - 484 (2002)

Van de Berg, W. D. J.; Paschen, W.; Scheepens, A.; Steinbusch, H. W. M.; Blanco, C. E.: Hypothermia prevents gene response induced by perinatal asphyxia. Pediatric Research 51 (4 Suppl. S), p. 2643 - 2643 (2002)